As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. Daily Tadalafil use is usually associated with lower incidents and severity of side effects compared to as-needed Tadalafil dosing.
Most common Tadalafil side effects
Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:
For a complete list of possible side effects,.
Possible drug interactions
Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.
On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.
For a complete list of possible drug interactions,.
Other important safety information
Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.
After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.
Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or healthcare provider.
Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The aim of this study was to explore the association between tadalafil and tadalafil plasma concentrations of tadalafil in patients with benign prostatic hyperplasia (BPH).
We conducted a retrospective cohort study to assess the association between tadalafil and tadalafil plasma concentrations in patients with BPH and patients with mild to moderate benign prostatic hyperplasia (MAH). We analyzed the association between tadalafil and tadalafil plasma concentrations in both the presence and absence of BPH and patients with mild to moderate BPH. This study was approved by the institutional review board of the University of Zhejiang Medical University and the Ethics Committee of the Medical Faculty of Zhejiang Medical University, Zhejiang, People's Republic of China. The study protocol was signed by the research team. Patients who had BPH were enrolled into the study. The tadalafil group (n=10) were excluded because of a significant decline in their prostate volume (p<0.05), anuria (p<0.05), and the presence of BPH (p=0.05).
There were no significant differences in the baseline characteristics between the two groups. However, the median serum tadalafil concentration was significantly higher in the tadalafil group (p<0.05). The mean concentration of tadalafil in the presence of BPH was significantly higher than that in the absence of BPH (p=0.038).
Tadalafil had a significant association with serum tadalafil concentrations in patients with BPH. This suggests that tadalafil may be an effective treatment for BPH in patients with BPH.
This study has limitations. The participants were recruited through advertisements in advertisements in public places and health centers. We cannot establish causality between tadalafil and tadalafil concentrations. The current study has several limitations. Firstly, the use of noninvasive tests is essential to assess the effects of tadalafil on a specific population. Second, we do not have a general understanding of the effect of tadalafil on the plasma concentration of tadalafil. Third, there is a lack of control group of patients with BPH who had BPH without any previous history of BPH. Fourth, the study was limited by a single-center design. We lack information regarding the effects of tadalafil on the plasma concentration of tadalafil.
The authors declare no conflict of interest.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License () which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Citation:Dong X, Liu W, Zhu L, et al. The association between tadalafil and tadalafil plasma concentrations in patients with BPH. PLoS ONE 12(4): e0267523.
Keywords:benign prostatic hyperplasia, tadalafil, benign prostatic hyperplasia, benign prostatic hyperplasia, prostate cancer, benign prostatic hyperplasia, tadalafil, plasma concentration, plasma tadalafil, tadalafil, tadalafil, plasma tadalafil, benign prostatic hyperplasia, prostate cancer, benign prostatic hyperplasia
This work was supported by the Natural Science Foundation of Shandong, China. We thank Chen Wang for his valuable comments.
Conflict of interest: none declared
Abbreviations:CAL, corticosteroid; CVD, cardiovascular disease; CEP, chronic obstructive pulmonary disease; CTD, corticotrophin-releasing hormone, D, diuretic; FPG, fasting plasma; HPF, high-density lipoprotein cholesterol; HbA1c, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; MOH, menopausal symptoms; NSAID, nonsteroidal anti-inflammatory drug; PSA, prostate-specific antigen; TTE, tadalafil; TSH, thyroxine
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Tadalafil works by making it more effective for blood flow to the penis by relaxing the muscles in the walls of these arteries. This can reduce blood pressure. When there is blood flow, that is considered to be erectile dysfunction, it works to increase the ability of the penis to cause and maintain an erection.
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Xanax, when used in excessive amounts can increase the risk of vision problems and increased pressure in the blood vessels and lungs. This is also known as dry mouth. While both medications can improve blood flow to the penis, they are not effective for all people and should not be taken with other medications that increase the risk of dry mouth or can increase the chance of sudden vision loss.
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Is sildenafil for pulmonary hypertension available onlinePulmonary hypertension is a condition in which your blood pressure is high enough that it causes your airways to narrow and breathing is difficult or impossible for you to make your breath from.
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